Computed tomography characteristics of patients with functional MR receiving MitraClip

Abstract Funding Acknowledgements Type of funding sources: None. Background Percutaneous leaflet repair with the MitraClip device (Abbott Vascular, Menlo Park, CA) is safe and effective in patients severe functional mitral regurgitation (FMR). Residual or recurrent MR may occur up to 40% associated persistent symptoms impaired survival. The anatomical characteristics residual after are not well defined by computed tomography angiography (CTA) FMR population. Methods A retrospective analysis significant FMR, who underwent retrospective-gated CTA at Minneapolis Heart Institute between July 2015 January 2020, identified those percutaneous MitraClip. Anatomical parameters were assessed pre-procedure compared without (?2) MR. Results total 25 included (median[Q1, Q3]; age, 80[75, 85]; 44% men) classified into ventricular (V-FMR, n = 12) atrial (A-FMR, 13) according CTA. 50% V-FMR 38% A-FMR had residual/worsening Among MR, shorter coaptation length was observed (2.2[2, 2.3] mm vs. 3.5[3, 4], p 0.006) (Figure). No differences seen patients. Conclusion Longer predictive successful procedure, whereas annulus size cardiac volumes not. <Ventricular FMR> Total (N residual/no worsening 6) Residual/worsening P value Septal-lateral diameter, 31.9 (30.5, 37.9) 32.2 (30.1, 39.8) (29.5, 35) 0.749 Annulus area, cm² 11.2 (10.4, 13.6) 11.3 (10.1, 14.6) 11.1 (9.6, 12.6) 0.631 Tenting 1.6 (1.3, 2.1) (1.2, 2.2) 1.7 2.3) 0.873 height, 8.5 (6.5, 9.7) (6.6, 9.3) 8.3 (6.3, 10.1) Coaptation length, 2.6 (2.1, 3.5) 3.5 (3.0, 4.0) 2.2 (2.0, 0.006 <Atrial 8) 5) 32.3 39.0) 32.0 (29.2, 39.9) 34.3 (30.8, 39.02) 0.464 10.3 (9.2, 14.7) 10.2 (9.0, 12.4 (9.4, 0.661 1.2 (0.8, 1.8) 1.1 (0.7, 1.3 0.884 5.5 (4.1, 6.9) 6.3 8.7) 4.6 (3.7, 5.8) 0.213 2.3 (1.5, 2.8) 2.5 (1.4, 1.9 2.6) Comparison baseline CT no residual/ Figure.